Should carrier dogs be bred? What ethical framework should guide breeding decisions when a dog carries the CEA mutation? A veterinary ophthalmologist's perspective on balancing breed health, genetic diversity, and responsible breeding practice.
Collie Eye Anomaly in Border Collies differs in important ways from other affected breeds. Exploring prevalence figures, working dog implications, breed-specific testing strategies, and how the working Border Collie community approaches CEA management.
A deep dive into the molecular biology behind Collie Eye Anomaly. How the NHEJ1 gene deletion disrupts eye development, why the same mutation causes variable outcomes, and what this means for testing and breeding.
Why the same NHEJ1 mutation produces vastly different clinical outcomes. Exploring the modifier genes that influence Collie Eye Anomaly severity, current research findings, and implications for future genetic testing and breeding decisions.
Comprehensive guide to DNA testing for Collie Eye Anomaly. Comparing laboratories, understanding the NHEJ1 mutation, interpreting results, and why genetic testing complements clinical examination.
